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Via US Weekly:

Stars' Soap Opera Beginnings: Josh Duhamel

Josh Duhamel

Fergie‘s husband played Leo du Pres on All My Children from 1999-2002. Duhamel reprised his role in August 2011, shortly before the show went off the air.
Stars' Soap Opera Beginnings: Sarah Michelle Gellar

Sarah Michelle Gellar

From 1993-1995, Gellar played Kendall Hart on ABC’s All My Children, which scored Gellar her first and only Daytime Emmy Award. She eventually reprised the role in 2011.
Stars' Soap Opera Beginnings: Laurence Fishburne

Laurence Fishburne

From 1973-1976, Fishburne had a supporting role as Dr. Josh Hall on One Life to Live.
Stars' Soap Opera Beginnings: Hayden Panettiere

Hayden Panettiere

The future Heroes star played Sarah Roberts on ABC’s One Life to Live from 1994–1997. Panettiere then took on the role of Lizzie Spaulding on CBS’ Guiding Light. After three years, she left the series in 2000.


Stars' Soap Opera Beginnings: Tommy Lee Jones

Tommy Lee Jones

The actor played Dr. Mark Toland on ABC’s One Life to Live. In one episode, his character married Julie Siegel, played by Lee Warwick.


Stars' Soap Opera Beginnings: Marcia Cross

Marcia Cross

One year after Cross appeared on the soap opera The Edge of Night, the actress was cast as Kate Sanders on One Life to Live. She remained on the show from 1985-1986 until she was cast on her third soap, Another World.
Stars' Soap Opera Beginnings: Ryan Phillippe

Ryan Phillippe

Long before he became a movie star, Phillippe appeared in 13 episodes of One Life to Live as Billy Douglas. Phillippe reprised his role one final time on January 9, 2012.

Stars' Soap Opera Beginnings: Kelly Ripa

Kelly Ripa

Ripa played played Hayley Vaughan for 12 years on All My Children. During her time on the show, she fell in love with one of her costars, Mark Consuelos. They eloped on May 1, 1996.